Efeito do óleo essencial dos frutos de aroeira vermelha (Schinus terebinthifolius Raddi) no período pré-implante de ratas prenhes
Oliveira, Moema Sousa DeRodrigue, Karoline FigueredoSousa, Marina Rebeca Soares Carneiro DeOliveira, Jamylla Mirck Guerra DeLira, Silvéria Regina De SousaFernandes, Maria Zenaide De Lima Chagas MorenoFernandes, Rozeverter Moreno
Medicinal plants are important for supplying raw materials for the synthesis of drugs and may also betoxic. The species Schinus terebinthifolius Raddi, popularly known as aroeira red or pink pepper is widelyconsumed by many people. This study aimed to assess adverse effects of the essential oil from the fruits ofSchinus terebinthifolius on pregnancy, administered during the preimplantation period. We used 32 pregnantanimals divided into four groups, a control (Tween 80) and three treated oil at doses of 25mg / kg, 50mg / kgand 100mg / kg treated once daily, the first to the seventh day of pregnancy, orally. Statistically there was nodifference between the treated groups compared to pre-implant loss, but there was a statistically significantdifference with respect to the increased weight of the empty uterus, both in relative mass as absolute. It isconcluded that the rats treated with oil of mastic-red fruits showed signs of gestational toxicity.(AU)
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