Efeito do captopril na maturação in vitro de oócitos bovinos
Sousa Junior, Antonio deBranco, Yndyra Nayan Teixeira Carvalho CasteloMota, Luiz Harliton Cavalcante MonteiroMoraes Junior, Felipe de JesusNascimento, Isolda Marcia Rocha doCosta, Amilton Paulo RaposoBranco, Marlon de Araújo CasteloSouza, Jose Adalmir Torres de
This study aimed to evaluate the effect of captopril on the in vitro maturation of oocytes. 1627 COCscattle slaughter houses were used, were subsequently screened, classified into grades I and II, according to themorphological quality, and submitted to the IVM process, distributed in four treatments: T1 - control; T2 - 5μMof captopril; T3 - 10μM of captopril; and T4 - 15μM of captopril, incubated in an incubator at 38.5 ° C with anatmosphere of 5% CO2. After 22 hours, the COCs were stripped to evaluate the rate of maturation, which wereas follows: T1 - 56.60% (120/212); T2 - 60.60% (240/396); T3 - 52.88% (174/329) and T4 - 58.30% (207/355).The results show that there was no statistically significant difference ( P> 0.05) between treatments duringmaturation, concluding that captopril supplementation did not affect the maturation of COCs.(AU)
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