Captopril na produção in vitro de embriões bovinos?
Sousa Junior, Antonio deBranco, Yndyra Nayan Teixeira Carvalho CasteloMota, Luiz Harliton Cavalcante MonteiroMoraes Junior, Felipe de JesusNascimento, Isolda Marcia Rocha doCosta, Amilton Paulo RaposoBranco, Marlon de Araújo CasteloSouza, Jose Adalmir Torres de
Objective to evaluate the effect of captopril in vitro production of bovine embryos. 472 COCs were usedfrom abattoir ovaries, which were screened, sorted and selected in grades I and II, and submitted to the PIVprocess. The IVM treatments were added in the following concentrations: T1 - control; T2 - 5 mM of captopril;T3 - 10 uM of captopril; and T4 - 15 captopril uM, the COCs were subjected to IVM, IVF CIV. The results showthat there was no statistically significant difference (P > 0.05) between treatments during maturation. Thevariables studied were cleavage and blastocyst rates. The captopril supplementation did not improve (P > 0.05)G1 cleavage rate - 61.84%; G2 - 71.00%; G3 - 68.87%; and G4 - 56.90%. Supplementation of 20μM ofcaptopril influenced the amount of viable embryos.(AU)
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