Neutralization test in mice {MNT) using effective dose50 {ED 50) and lnternational Units {lU) on bovine"s sera vaccinated with an inactivated rabies virus vaccine

Albas, AvelinoEduardo Pardo, PauloGiometti, JoséBernardi, FernandaHonma lto, Fumio

The results of neutralization test in mice (MNT) performed on bovine"s sera that had been vaccinated previously with a commercialinactivated rabies vírus vaccine were calculated and expressed either in logarithm of Effective dose50 (ED 5J or in lnternationalUniVml (IU/ml). Statistical analysis revealed a Spearman nonparametric correlation of r= 0.6469, and when the use of IU/ml isimpeditive, the MNT titers expressed in ED 50 is still a useful procedure to determine if the bovines have responded to antirabies vaccination.