Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159

Park, Soon-NangAhn, Sug-JoonKook, Joong-Ki

In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.(AU)

1. Ursolic acid
2. Streptococcus mutans UA159
3. Peptidoglycan biosynthesis
4. Oleanolic acid