Antifungal activity of extracts from Piper aduncum leaves prepared by different solvents and extraction techniques against dermatophytes Trichophyton rubrum and Trichophyton interdigitale

Leite Santos, MaximillanFroés Magalhães, ChaianaBarcellos da Rosa, Marcelode Assis Santos, DanielGonçalves Brasileiro, BeatrizMachado de Carvalho, LeandroBarreto da Silva, MarceloLeomar Zani, CarlosPessoa de Siqueira, EzequiasLoreto Peres, RodrigoAssunção Andrade, Anderson

The effects of different solvents and extraction techniques upon the phytochemical profile and anti-Trichophyton activity of extracts from Piper aduncum leaves were evaluated. Extract done by maceration method with ethanol has higher content of sesquiterpenes and antifungal activity. This extract may be useful as an alternative treatment for dermatophytosis.

1. Trichophyton
2. dermatophytes
3. extraction techniques
4. Piper aduncum L.
5. antifungal activity