Bovine response to lipoarabinomannan vaccination and challenge with Mycobacterium paratuberculosis

Jolly, AnaMorsella, ClaudiaBass, LauraFiorentino, María AndreaPaolicchi, Fernando AlbertoMundo, Silvia Leonor

This study aimed to evaluate the immune response in bovines following immunization with a mycobaterial Lipoarabinomannan extract (LAMe) and the effect of Map challenge. LAMe vaccine induced specific antibody levels that diminished after the challenge and affected Map excretion at least for 100 days thereafter.

1. experimental challenge
2. paratuberculosis
3. humoral immune response
4. bovine
5. LAM