Detection of human cytomegalovirus and Epstein-Barr virus in coronary atherosclerotic tissue

Imbronito, Ana VitóriaMarcelino, Silvia LinardiGrande, Sabrina RosaNunes, Fabio DaumasRomito, Giuseppe Alexandre

Previous studies indicated that patients with atherosclerosis are predominantly infected by human cytomegalovirus (HCMV), but rarely infected by type 1 Epstein-Barr virus (EBV-1). In this study, atheromas of 30 patients who underwent aortocoronary bypass surgery with coronary endartherectomy were tested for the presence of these two viruses. HCMV occurred in 93.3 percent of the samples and EBV-1 was present in 50 percent of them. Concurrent presence of both pathogens was detected in 43.3 percent of the samples.

1. Epstein-Barr virus
2. Cytomegalovirus
3. Atherosclerosis