Oral administration of piperine for the control of aflatoxin intoxication in rats

Gagini, Thalita B.Silva, Robson E.Castro, Isabela S.Soares, Breno A.Lima, Marco E.F.Brito, Marilene F.Mazur, CarlosDireito, Glória M.Danelli, Maria das Graças M.

Aflatoxins are mycotoxins that have important toxic effects on human and animal health, even if consumed at low doses. The oral administration of piperine (1.12 mg/kg) during 23 days in rats seemingly interfered with the toxicity of aflatoxins, decreasing hepatic injuries and the leukocyte depletion in experimentally intoxicated animals.

1. aflatoxins
2. experimental intoxication
3. rats
4. piperine