Anti-Helicobacter pylori activity of plant extracts traditionally used for the treatment of gastrointestinal disorders

Lúcia Cogo, LauraLeise Bastos Monteiro, CristinaDallarmi Miguel, MarilisGomes Miguel, ObdulioMachado Cunico, MiriamLima Ribeiro, MarceloRamalho de Camargo, EloáMaria Botão Kussen, Gisleneda Silva Nogueira, KeiteMaria Dalla Costa, Libera

The antibacterial activity of plant extracts obtained from Bixa orellana L., Chamomilla recutita L., Ilex paraguariensis A. St.-Hil., Malva sylvestris L., Plantago major L. and Rheum rhaponticum L. has been evaluated against two reference strains and eleven clinical isolates of Helicobacter pylori. All the plant species chosen are used in popular Brazilian cuisine and folk medicine in the treatment of gastrointestinal disorders. Initial screening was made by the disk diffusion test and then minimum inhibitory concentration was determined by the agar dilution method. The results presented in this work demonstrated that among the plant preparations analyzed, B. orellana L., C. recutita L., I. paraguariensis A. St.-Hil. and M. sylvestris L. were capable of inhibiting the in vitro growth of H. pylori.

1. plant extracts
2. entibacterial activity
3. Helicobacter pylori