Metamizol and scopolamine for conventional or two-port laparoscopic-assisted ovariohysterectomy in dogs

Dalmolin, Fabíola; Oliveira, Marília Teresa; Pinto Filho, Saulo Tadeu Lemos; Vaz, Marcos André Braz; Bertoletti, Bianca; Pohl, Virgínia Heinz; Feranti, João Pedro Scussel; Hartmann, Hellen Fialho; Brun, Maurício Veloso

Metamizol and scopolamine for conventional or two-port laparoscopic-assisted ovariohysterectomy in dogs

Dalmolin, FabíolaOliveira, Marília TeresaPinto Filho, Saulo Tadeu LemosVaz, Marcos André BrazBertoletti, BiancaPohl, Virgínia HeinzFeranti, João Pedro ScusselHartmann, Hellen FialhoBrun, Maurício Veloso

Background: Ovariohysterectomy (OVH) is one of the most applied techniques in Veterinary Medicine. Despite some analgesic protocols being used after this procedure in order to control post operatory pain, there is a lack of knowledge of the efficacy after conventional and two port laparoscopic-assisted techniques in dog female. Although the combined formulation of metamizol and scopolamine is used, there is no knowledge about the efficacy and collateral effects in a 6 h regimen after OVH. The aim of this research was to evaluate the efficacy of metamizol and scopolamine to analgesia after two techniques of OVH in dog female. Materials, Methods & Results: Fifteen adults and healthy dog female were submitted to OVH, being eight to the conventional procedure and seven to video assisted technic with two ports. The patients received a combination of metamizol and scopolamine, 6-6 h during 48 h and were evaluated before surgery, 60 min after extubation and on 1 h interval during the f irst 8 h, and at 12, 18, 24, 36, 48 and 72 h after surgery. For this, the University of Melbourne Pain Scale (UMPS) and the short-form of the Glasgow Composite Measure Pain Scale (CMPS-SF) were applied by three evaluators blinded to surgical technic. Glucoses measurement was realized at 1, 6, 12, 24, 48 and 72 h after surgery. Analgesic rescue was not necessary for any animal. Punctuation of UMPS in GC decreases at 8 h and at 5 h, and to GV at 12 and 24 h. Difference between groups happened at 3 h with larger average to GV; at 48 h the punctuation in GC was lager. Considering CMPS-SF to CG, higher average was observed at 1 h and decreased at 2, 3, 8 and 18. At GV highest average points was verified at 1, 2 and 3 h and decreased at 5, 8 and 18 h. Correlation was strong and positive between each two evaluators. Animals of both groups had increased average...(AU)