Feline lymphoplasmacytic gingivostomatitis: clinical and anatomopathological aspects
Sakis, Eduardo RebelatoMachado, Tanise PolicarpoSetim, Diorges HenriqueMelatti, LucianeMotta, Adriana Costa da
Background: Feline lymphoplasmacytic gingivostomatitis (FLPG) is an idiopathic, multifactorial and highly challengingcondition, since the results of the available treatments are partial and transitory. A set of lesions triggered by inflammatoryreaction is observed, sometimes with ulcerations in the oral mucosa, leading to algia and discomfort. Histopathologicalexamination figures as the definitive diagnostic tool, presenting distinct cellular elements. The present study aims to reportthree cases of FLPG, firstly addressing the anatomopathological findings, as well as the therapeutic approach used andthe results obtained in each case.Cases: Case 1- Occurred in a feline Siamese male 15-year-old, weighing 3.8 kg, which was admitted at a local clinic, underthe complaint of prostration, dysphagia, and weight loss, signs that were noticed approximately 5 days before. Clinicalevaluation revealed multiple proliferative and ulcerative lesions, extending until the isthmus of the fauces, erythematousareas around the teeth and multifocal gingival reabsorption. Once the clinical signs and lesions were observed, samples werecollected for histopathological examination and sent to the Laboratory of Animal Pathology (LAP) of Faculty of Agronomyand Veterinary Medicine of the University of Passo Fundo (FAVM-UPF). Histologically, both fragments presented lymphoplasmacytic infiltration, with large and intensely eosinophilic cytoplasm, often with granular aspect, central to lateralizedhyperchromatic nuclei, located predominantly in lamina propria and mucosa, as well as a discrete Mott cell infiltrate. Itwas also observed the presence of diffuse suppurative chronic inflammatory infiltrate, predominantly in lamina propriaand mucosa, as well as foci of edema and hemorrhage, in addition to loss of tissue architecture establishing the definitivediagnosis of...(AU)
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