Ependimoma anaplásico em cão
Andrade, Thamara MatosCaramalac, Silvana MarquesPupin, Rayane ChitolinaBabo-Terra, Veronica JorgePalumbo, Mariana Isa Poci
Background: Anaplastic ependymoma is a rare primary intracranial neoplasm in dogs and cats, which originates fromependymal cells that line the ventricular system of the brain and spinal cord. Normally, this neoplasm occurs as a single,expansive mass that develops mainly in the lateral ventricles, and neurological changes are due to local tissue impairmentand peritumoral tissue compression. This article reports a case of anaplastic ependymoma in a dog treated at the VeterinaryHospital of the Federal University of Mato Grosso do Sul (UFMS), emphasizing and describing the neurological signsand histopathology of this tumor.Case: This article reports the case of a 11-year-old mongrel dog with a history of butting its head against obstacles, ofcompulsive walking, and altered proprioception of the right side limbs. The condition evolved to positional strabismus ofthe left eye, left lateral deviation of the head, vertical nystagmus, decreased level of consciousness, and constant lateraldecubitus. Due to the suspicion of intracranial neoplasia and worsening of its clinical condition, the animal was euthanized. Necropsy of its body revealed a mass of approximately 3 cm in diameter in the third ventricle (in the left lateralregion). A histological examination revealed random clusters of ependymal cells with a few rosettes and pseudorosettes.The cells were cuboid to cylindrical in shape, with moderate eosinophilic cytoplasm with indistinct borders, and round tooval moderately hyperchromatic nuclei with 1-2 visible nucleoli. Based on these findings, the tumor was characterized asanaplastic ependymoma.Discussion: Intracranial tumors occur more frequently in older animals, and usually neurological signs tend to evolve progressively. Most affected dogs are mongrels, like the dog described in this report, but Golden Retrievers, Boxers, LabradorRetrievers...(AU)
Texto completo