Osteopatia hipertrófica secundária a osteossarcomacondroblástico extraesquelético em um cão
Hoffmann, Natalia MartinsLuz, Mayron Tobias daVieira, Luisa LemosSilveira, Matheus FolgeariniCorrêa, Pâmela da SilvaOliveira, Débora Maria Marques Callado de
Background: hypertrophic osteopathy is a periosteum disturb characterized by diffuse new bone formation which leads tosignificant thickening and deformity of members. Secondary in nature, it usually follows large pulmonary lesions such asabscesses and neoplasms. Extraskeletal osteosarcomas are rare and extremely malignant mesenchymal neoplasms. Theycomprise approximately 1% of all domestic animals osteosarcomas and develop in the absence of a primary bone lesion.The aim of this paper was to describe a case of hypertrophic osteopathy, involving joints and upper limbs bones includingilium, secondary to a mediastinal chondroblastic osteosarcoma with pulmonary metastasis.Case: A 10-year-old spayed female mixed breed dog, weighing 9 kg, was presented with painful limbs, lameness, hind limbsswelling and a four-month history of weight loss. Radiographic examination revealed bilateral and asymmetric periostealreactions on diaphyseal and/or epiphyseal areas of all proximal phalanges; metacarpal, metatarsal, carpal and tarsal bones;radius; ulna; tibia; fibula; humerus; femur and right ilium. An increased soft tissue radiopacity was noted on the lateral sideof the right knee joint. Thoracic radiographies and ultrasonography suggested the presence of a 5-cm neoplasm or abscessin the left caudal lung lobe. At necropsy, the lobe showed a firm and solid, oval white mass measuring 5.2 x 2.9 cm. Anothermass was found in the caudal mediastinum, near the diaphragm, with same color and more irregular aspect, measuring 3.3cm of diameter. Intense periosteal new-bone formation was seen in the entire length of the four limbs bones, characterizedby thickening of the bone surface and formation of irregular trabeculae perpendicular to the cortex. Significant swelling andthickening of the joint capsule was noted in the right knee. There was no microbial growth on aerobic or anaerobic culturesfrom the masses samples sent to culture. [...](AU)
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