Platelet rich plasma intralesional injection as bedside therapy for tendinitis in athletic horse
Bazzano, MarilenaPiccione, GiuseppeGiannetto, ClaudiaTosto, FrancescoDi Pietro, SimonaGiudice, Elisabetta
Background: Tendinitis result in a considerable economic loss to the equine industry due to decreased performance, prolonged rehabilitation, recurrent injuries and early retirement. It is well known that damaged tendons have a low healing potential and old therapies often lead to mechanical side effect of a scar tissue with reduced functionality and high risks of re-injury. Regenerative therapies that induce the restoration of the tendons normal structure and function, rather than formation of less functional scar tissue, decrease the risk of re-injury tissue repair. In particular, platelet rich plasma (PRP) therapy reproduce those processes of development in which there are spatial and temporal interactions between scaffold, growth factors and cell populations that lead to a normal structure and function of neo-formed tendon tissue. According to this knowledge, the aim of this study was to assess autologous PRP therapy as bedside procedure to treat equine tendon injuries. Materials, Methods & Results: Following a clinical and ultrasound examination, fifteen Thoroughbred horses affected by tendinitis of the superficial or deep digital flexor tendons were treated with intralesional injection of autologous PRP on-field preparation. On each horse blood samples were aseptically collected from the jugular vein into sterile tubes. Two sequential centrifugations of whole blood, a
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