Outbreak of porcine epidemic diarrhea in piglets in Gansu Province, China
Wang, HuiXia, XinchaoLiu, ZhiqiLiu, YongmingWang, ShengyiQi, ZhimingLiu, ShixiangWang, HaijunNiu, XuLiu, Shanshan
Background: Porcine epidemic diarrhea virus (PEDV) is a member of the genus Coronavirus and family Coronaviridae. The virus is the aetiological agent of porcine epidemic diarrhea (PED), and detected for the first time in 1978 in England. PED causes acute enteritis and severe diarrheal disease with high mortality, particularly in suckling piglets; massive economic losses in many locations resulted. The severe acute diarrhea outbreak associated with high morbidity and mortality. By now, PEDV cases confirmed by laboratory testing have been reported from a lot of countries (southern China, Thailand, Vietnam, Korea and Japan). Gansu is located in the northwest of China; and few case of PEDV infection has been detected. And previous research has shown that the immunity induced by the commercial Korean vaccine do not provide cross-protection to the recent Chinese PEDV strain. So the virus may as a variant PEDV emerging in Gansu. The study was aimed at detecting the presence of piglets positive to PEDV in Gansu province of China. Materials, Methods & Results: A total of 120 samples were collected from piglets from different farms in Gansu province, China from March 2011 to December 2012. The clinical symptoms and anatomic pathological changes of diarrheal piglets were observed. The total RNA was extracted from intestinal contents of diarrheal suckling piglets with a commercial High
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