Nonsuppurative myocarditis associated with bovine viral diarrhea virus infection in calves in the state of Mato Grosso do Sul, Brazil
Paula Pinto, AnaSilva Santos, BethaniaLilge Kawski de Sá Ribas, NickollyBarbieri Bacha, FláviaMarques Carvalho, NiltonDriemeier, DavidAline Bobbi Antoniassi, NadiaAntonio Amaral Lemos, Ricardo
Background: Bovine viral diarrhea virus (BVDV) refers to a heterogeneous group of viruses belonging to the family Flaviviridae and genus Pestivirus. This family of viruses is one of the main pathogens of cattle and causes significant economic losses to the cattle industry worldwide. BVDV is an enveloped virus with a diameter of 45 nm and single-stranded RNA genome of 12.5 kb. BVDV infection has been associated with a number of clinical manifestations ranging from unapparent infection and mild signs to acute illness and death. In general, calves are more susceptible to BVDV infection, but adult cattle can develop the clinical disease if they are infected with highly virulent virus strains. This study describes clinical, anatomopathological and epidemiological findings of a BVDV outbreak in calves in the state of Mato Grosso do Sul, Brazil. Materials, Methods & Results: The outbreak occurred in the town of Agua Clara in the state of Mato Grosso do Sul. Epidemiological and clinical data were collected by the farm manager during a visit to the property. The outbreak involved two Nelore heifer calves that died between 30 and 40 days of age. One calf was taken to the Laboratory of Pathological Anatomy (LAP) of the Faculty of Veterinary and Animal Husbandry, Federal University of Mato Grosso do Sul (FAMEZ/ UFMS). The calf was necropsied, and white streaks were seen on the heart, i
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