Cortical necrosis and cerebral atrophy in calves experimentally infected with bovine herpesvirus type 5
Spilki, Fernando RosadoEsteves, Paulo AugustoSilva, Tamir Calcagnotto daFranco, Ana CláudiaDriemeier, DavidRoehe, Paulo Michel
Bovine encephalitis herpesvirus, or bovine herpesvirus type 5 (BoHV-5), a member of the family Herpesviridae, subfamily Alphaherpesvirinae, is long recognized as the causative agent of bovine herpesvirus encephalitis. The disease caused by BoHV-5 is characterized by signs of nervous impairment, consequent to non-suppurative meningoencephalitis. Although bovine herpetic encephalitis is a rare event in herds from the Northern Hemisphere, BoHV-5 infections are an important cause of central nervous system disease in cattle in Brazil and Argentina. Recovery of animals from clinical illness has been documented before, both in naturally infected animals and experimentally infected individuals.[...](AU)
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