Chemical castration of male dogs... myth or reality?
Oliveira, Érika Christina SantosMuller, Patricia MarinhoSilva, Fernanda Lavínia MouraMoura, Maria RaquelSá, Marcelo Jorge Cavalcanti deMarques Junior, Antônio de Pinho
Background: Fertility control of animals by nonsurgical methods has been pursued to prevent unwanted pregnancies and suppress testosterone-dependent traits in farm and companion animals. In the latter, injection of sclerosing agents into the testis had considerable potential as a candidate for chemical sterilization of dogs. This article aims to review the potential of this new non-surgical technology for sterilization of male dogs. Review: Investigations of contraceptive agents for male dogs where initiated only in the last decade. Chemical sterilization is a solution for pet overpopulation and for non-surgical methods of male contraception. A variety of compounds have been tested, some of which were either safe but not effective or vice versa. The ideal chemical sterilization needs to meet three key criteria to be regarded as a good alternative to surgical sterilization. First, it has to be effective in a high percentage of treated animals. Secondly, it should have a high margin of safety for treated animals and the environment. Third, it has to be permanent and irreversible following a single treatment. The first product obviously fulfilling these criteria was zinc gluconate. Conclusion: Intratesticular injection of a zinc gluconate-based solution has great potential as a permanent contraceptive for dogs.
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